Institute for Medical Technology Assessment (iMTA)
Over 20 years iMTA researchers have established a reputation for thorough scientific research and methodological innovation in economic evaluation and patient reported outcomes research to support reimbursement policy making. Major activities are the design, conduct and analysis of applied economic evaluations. This includes economic evaluations as part of randomised clinical trials, decision analytic modelling and economic and statistical evaluation of observational data sets. Ongoing projects cover disease areas such as cancer, cardiovascular disease, diabetes, asthma and COPD, rheumatology, musculoskeletal disease and various orphan diseases. Key themes of methodological research include research to support decision making on new medical technologies, analytical issues of dealing with uncertainty and the value of additional research, preference and utility measurement, challenges in analysing observational data, informal caregiver burden, estimating productivity loss (friction cost approach), costs and outcomes during life years gained and end-of-life costs. Current research projects within the policy support theme focus on implementation of the proportional shortfall concept, coverage-with-evidence development, measuring the value of a QALY, value-based pricing and multi-criteria decision analysis.